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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. An article in a clinical pharmacology journal describes a double-blind controlled trial comparing the efficacy of sumatriptan to a placebo injection for intractable migraine which used a 5 point Likert scale to evaluate headaches 2 hours after treatment. Which of the following is the most appropriate statistical test for analyzing the data?

A) Student's t test
B) Chi-square test
C) Mann-Whitney U test
D) Fisher's exact test

2. Upon reviewing a clinical trial submission for publication, it is discovered that the authors have asked a medical Writer to help develop the manuscript after the data have been collected and analyzed by the authors. The medical Writer developed the manuscript, and the authors reviewed and edited the document before submitting it for publication. What is the most appropriate action for the authors to take?

A) List the medical Writer as an author.
B) Name the medical Writer in the acknowledgements section.
C) Do not identify the medical Writer.
D) The article should not be published.

3. A patient presents at a physician's office with gait unsteadiness and clumsiness. The patient has a history of type 2 diabetes mellitus, hypertension, and chronic numbness and tingling of the feet and fingertips.
Examination reveals mild distal wasting, glove-and-stocking sensory impairment, absent ankle jerks, brisk knee jerks, and bilateral Babinski reflexes. Gait is slightly ataxic.
CBC reveals a hemoglobin of 10.1 g/dL, WBC of 4,500 cells/mL, MCV 120 fL, and platelets
163,000 cells/ul.
Which of the following is the most important laboratory test for assisting in diagnosis?

A) Serum vitamin B12
B) Folic acid
C) Erythrocyte sedimentation rate
D) Ferritin

4. A 53-year-old patient with an 8-year history of diabetes is currently taking glipizide 10 mg twice daily before breakfast and supper. The patient weighs 85 kg and reports a 4.5 kg weight gain in the last year. Laboratory results are:
Creatinine: 1.2 mg/dL
A1C: 8.5%
What is the most appropriate recommendation at this time for improved diabetes control?

A) Continue with glipizide and add metformin.
B) Increase glipizide to 20 mg twice daily.
C) Change glipizide to insulin.
D) Change glipizide to metformin.

5. Which statement is correct regarding the measurement of blood pressure, according to the American Society of Hypertension?

A) The patient should not smoke for at least 10 minutes prior to measurement.
B) The patient should stand with arms bared during measurement.
C) Two or more readings taken 2 minutes apart should be averaged.
D) The patient should be seated at least 10 minutes prior to measurement.

Solutions: